名称:5-氧代-2-氮杂双环[2.2.1]庚烷-2-羧酸叔丁酯

英文名称:tert-butyl 5-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate

分子式:c11h17no3

分子量: 211.26
cas no.:198835-06-2
结构式:image.png

规格:95%

用途:基础原料、有机中间体、医药中间体

合成路线如下:

diborane;

reactants are commercially availlable.
slade, david j., us2011/144150, a1, (2011) in a method analogous to j.malpass and c. cox, tetrahedron lett., 1999, 40, 1419-1422, tert-butyl 2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate is treated with diborane to afford a mixture of alcohols w hich is separated by chromatography.the desired alcohol tert-butyl 5-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate is then oxidized using the swern procedure to afford the title compound.


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