名称：5-甲基-吡啶-2-基)甲醇
英文名称：(5-methylpyridin-2-yl)methanol
分子式：c7h9no
分子量: 123.16
cas no.：22940-71-2
结构式：
外观：黄色液体
规格：95%
用途：基础原料、有机中间体、医药中间体
合成路线如下：
acetic anhydride; hydrogenchloride; water;
reactants can be synthesized in 1 step.
gallaschun, randall, wo2014/143799, a2, (2014) step 2 (5-methylpyridin-2-yl)methanol 2, 5-dimethylpyridine 1 -oxide (2.5g, 20.3 mmol) was added to acetic anhydride (8.2ml) at 100 °c over a period of 30 min. then the mixture was refluxed 1 h. the m ixture was cooled to room temperature and carefully quenched with ethanol (1 lml). the reaction mixture was concentrated. the residue was treated with in hc1 (6 ml) and refluxed 1 h. the reaction was concentrated and the residue was partitioned between ethyl acetate and water. the organic phase was dried over sodium sulfate, filtered and concentrated to give (5-methylpyridin-2-yl) methanol (2g, 80 .0percent yield) as a light yellow oil. lcms mh 124.