n-氧化胺用一个如乙酸酐那样的活化剂处理,重排产生n,n-二取代酰胺和醛。
反应机理
分子内路径也有可能
反应实例
参考文献
1. (a) pinner, a.; klein, f. ber.1877, 10, 1889–1897. (b) pinner, a.; klein, f. ber.
1878, 11, 1825.
2. poupaert, j.; bruylants, a.;crooy, p. synthesis 1972, 622–624.
3. lee, y. b.; goo, y. m.; lee,y. y.; lee, j. k. tetrahedron lett. 1990, 31, 1169–1170.
4. cheng, c. c. org. prep.proced. int. 1990, 22, 643–645.
5. siskos, a. p.; hill, a. m. tetrahedronlett. 2003, 44, 789–794.
6. fischer, m.; troschuetz, r. synthesis2003, 1603–1609.
7. fringuelli, f.; piermatti,o.; pizzo, f. synthesis 2003, 2331–2334.
8. cushion, m. t.; walzer, p.d.; collins, m. s.; rebholz, s.; vanden eynde, j. j.;
mayence, a.; huang, t. l. antimicrob.agents chemoth. 2004, 48, 4209–4216.
9. li, j.; zhang, l.; shi, d.;li, q.; wang, d.; wang, c.; zhang, q.; zhang, l.; fan, y.
synlett 2008, 233–236.
10. racané, l.;tralic-kulenovic, v.; mihalic, z.; pavlovic, g.; karminski-zamola, g.
tetrahedron 2008, 64, 11594–11602.
11. pfaff, d.; nemecek, g.;podlech, j. beilstein j. org. chem. 2013, 9, 1572–1577.
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