名称：2-(3-羟基苯基)乙醇
英文名称：3-hydroxyphenethyl alcohol
分子式：c8h10o2
分子量: 138.16
cas no.：13398-94-2
结构式：
外观：红棕色透明液体
规格：97%
用途：基础原料、有机中间体、医药中间体
合成路线如下：
borane-thf; tetrahydrofuran;
reactants are commercially availlable.
sumitomo pharmaceuticals company, limited, ep1386913, a1, (2004) example 10-1 preparation for 2-(3-hydroxyphenyl)ethanol to a solution of 3-hydroxyphenylacetic acid (3.04g, 20.0mmol) in tetrahydrofuran (30ml) was added at 0 °c borane-tetrahydrofuran complex (1m, 30.0ml, 30.0mmol) under an atmosphere of n itrogen.. the mixture was stirred for 1 hour, followed by addition of water and the mixture was extracted with ethyl acetate.. the organic layer was dried over magnesium sulfate, filtered and concentrated to give the subject compound (2.76g , 100percent).1h nmr (cdcl3, 400 mhz) delta 7.19 (t, 1 h, j = 7.4 hz), 6.80 (d, 1 h, j = 7.4 hz), 6. 72 (s, 1 h), 6. 70 (d, 1 h, j = 7. 4 hz), 3.86 (t, 2 h, j = 6.5 hz), 2.83 (t, 2 h, j = 6.5 hz).